OXYMETAZOLINE (OX ee me TAZ oh leen) treats a runny or stuffy nose. It may also be used to treat sinus congestion and pressure. It is often used for a short period of time. It works by decreasing swelling in the nose, making it easier to breathe. It belongs to a group of medications called decongestants.

How should I use this medication?

This medication is for use in the nose. Take it as directed on the label. Shake well before using. Do not use it more often than directed. Do not use for more than 3 days in a row without talking to your care team first. Make sure that you are using your nasal spray correctly. Ask your care team if you have any questions. Talk to your care team about the use of this medication in children. While it may be given to children as young as 2 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

Where should I keep my medication?

Keep out of the reach of children and pets. Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date. To get rid of medications that are no longer needed or have expired: -Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location. -If you cannot return the medication, ask your pharmacist or care team how to get rid of this medication safely.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible: -Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome): -Dryness or irritation inside the nose -Sneezing -Worsening runny or stuffy nose

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions: -Diabetes -Glaucoma -Heart disease -High or low blood pressure -History of stroke -Raynaud's phenomenon -Scleroderma -Sjogren's syndrome -Thromboangiitis obliterans -Thyroid disease -Trouble urinating due to an enlarged prostate gland -An unusual or allergic reaction to oxymetazoline, other medications, foods, dyes, or preservatives -Pregnant or trying to get pregnant -Breast-feeding

What may interact with this medication?

This medication may interact with the following: -Certain medications for an enlarged prostate, such as alfuzosin, doxazosin, prazosin, and terazosin -Certain medications for blood pressure and heart disease, such as ace-inhibitors, beta-blockers, calcium-channel blockers, digoxin, and diuretics -MAOIs, such as isocarboxazid, phenelzine, rasagiline, selegiline, and tranylcypromine -Nafarelin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse. To prevent the spread of infection, do not share this medication with anyone else.