Latisse contains bimatoprost, a synthetic prostaglandin analog, in the form of an ophthalmic solution with a concentration of 0.03%. It is available as a clear, isotonic, colorless, sterile solution. The inactive ingredients include benzalkonium chloride, citric acid, purified water, sodium chloride, and sodium phosphate dibasic. The solution is administered to the eye.

How should I use this medication?

This medication is only for use on the skin of the upper eyelid margins at the base of the eyelashes. Do not use in the eye or on the lower eyelid. Do not take by mouth. Follow the directions on the prescription label. Wash face and remove makeup and contact lenses before use. Use the applicators supplied with your medication to apply the drops. Use a different applicator for each eye; do not use each applicator more than once. Do not touch the tip of the dropper or applicator. After applying 1 drop of solution to the applicator, evenly apply along the skin of the upper eyelid margin at the base of the eyelashes. Blot excess medication with a tissue or absorbant cloth. Use your doses at regular intervals. Do not use your medication more often than directed. If you are using another eye product, wait at least 5 minutes between use of this medication and the other eye product. Talk to your care team about the use of this medication in children. While this medication may be prescribed for children as young as 5 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

Where should I keep my medication?

Keep out of the reach of children. Store this medicine between 2 and 25 degrees C (36 and 77 degrees F). Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible: -Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat -Change in vision -New or worsening eye pain, redness, irritation, or discharge Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): -Change in eye, eyelash, or eyelid color -Dry eyes -Eye irritation or itching -Increased tears after use

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions: -Eye inflammation -Glaucoma -Macular edema -An unusual or allergic reaction to bimatoprost, other medications, foods, dyes, or preservatives -Pregnant or trying to get pregnant -Breast-feeding

What may interact with this medication?

-Medications used in the eye to treat glaucoma or high eye pressure (i.e., Lumigan, latanoprost, travoprost or unoprostone)

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

This medication may cause your eyelids and the colored part of your eye to get darker. Your eyelids may return to their normal color several weeks or months after you stop using this medication. The change in the colored part of the eye may be permanent. You may experience hair growth on other areas of the skin that this medication frequently touches. You can reduce the chances of this happening by blotting away any excess medication with a tissue or other absorbent material. There may be a difference in eyelash length, thickness, fullness, color, number of eyelash hairs, and/or direction of eyelash growth between eyes. This will usually go away if you stop using this medication. If you wear contact lenses, take them out before using this medication. Contact lenses may be put back in after 15 minutes.