VYVGART contains the active ingredient efgartigimod alfa-fcab, which is a human immunoglobulin G1 (IgG1)-derived Fc fragment. This drug is provided as a sterile, preservative-free injectable solution intended for infusion, with each single-dose vial containing 400 mg of efgartigimod alfa-fcab at a concentration of 20 mg/mL. The formulation is clear to slightly opalescent and colorless to slightly yellow.
How should I use this medication?
This medication is infused into a vein. It is given by your care team in a hospital or clinic setting. Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.
Where should I keep my medication?
This medication is given in a hospital or clinic. It will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible: -Allergic reactions or angioedema—skin rash, itching or hives, swelling of the face, eyes, lips, tongue, arms, or legs, trouble swallowing or breathing -Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell -Infusion reactions—chest pain, shortness of breath or trouble breathing, feeling faint or lightheaded Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome): -Burning or tingling sensation in hands or feet -Headache -Muscle pain
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions: -Immune system problems -Infection -Kidney disease -An unusual or allergic reaction to efgartigimod alfa, other medications, foods, dyes, or preservatives -Pregnant or trying to get pregnant -Breast-feeding
What may interact with this medication?
-Eculizumab -Immune globulin -Live virus vaccines -Ravulizumab -Rozanolixizumab
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse. Your condition will be monitored carefully while you are receiving this medication. This medication may increase your risk of getting an infection. Call your care team for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.
Source: This information is sourced from Elsevier Inc.
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