Trulance contains the active ingredient plecanatide, which is a guanylate cyclase-C agonist. It is available in the form of 3 mg tablets for oral administration. The tablets include inactive ingredients like magnesium stearate and microcrystalline cellulose.
How should I use this medication?
Take this medication by mouth with a full glass of water. Take it as directed on the prescription label at the same time every day. Do not cut, crush or chew this medication. Swallow tablets whole. You can take it with or without food. If it upsets your stomach, take it with food. Keep taking it unless your care team tells you to stop. A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time. Talk to your care team about the use of this medication in children. It is not approved for use in children.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, skip it. Take your next dose at the normal time. Do not take extra or 2 doses at the same time to make up for the missed dose.
Where should I keep my medication?
Keep out of the reach of children and pets. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep this medication in the original container. Protect from moisture. Keep container tightly closed. Do not throw out the packet in the container. It keeps the medication dry. Get rid of any unused medication after the expiration date. To get rid of medications that are no longer needed or have expired: -Take the medications to a medication take-back program. Check with your pharmacy or law enforcement to find a location. -If your cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, take the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible: -Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat Side effects that usually do not require medical attention (Report these to your care team if they continue or are bothersome): -Diarrhea -Dizziness -Nausea -Sore throat -Runny or stuffy nose
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions: -Now have diarrhea or have diarrhea often -Stomach or intestinal disease, including bowel obstruction or abdominal adhesions -An unusual or allergic reaction to plecanatide, other medications, foods, dyes, or preservatives -Pregnant or trying to get pregnant -Breast-feeding
What may interact with this medication?
-Certain medications for bowel problems or bladder incontinence (these can cause constipation)
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not get better or if they get worse. Diarrhea is a common side effect of this medication. It often begins within 2 weeks of starting this medication. Stop taking this medication and call your care team if you get severe diarrhea.
What are the most serious risks of this medication?
NEVER give this medication to children younger than 6 years of age. It may cause serious dehydration and harm. Older children may also be at risk.
Source: This information is sourced from Elsevier Inc.
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