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Unithroid contains the active ingredient levothyroxine sodium, which is a form of L-thyroxine (T4) in the sodium salt form. It is available as tablets for oral use in various strengths, including 25 mcg to 300 mcg. Key inactive ingredients include corn starch, croscarmellose sodium, and magnesium stearate.
How should I use this medication?
Take this medication by mouth with plenty of water. It is best to take on an empty stomach, at least 30 minutes to one hour before breakfast. Avoid taking antacids containing aluminum or magnesium, simethicone, bile acid sequestrants, calcium carbonate, sodium polystyrene sulfonate, ferrous sulfate, sevelamer, lanthanum, or sucralfate within 4 hours of taking this medication. Follow the directions on the prescription label. Take at the same time each day. Do not take your medication more often than directed. Contact your care team regarding the use of this medication in children. While this medication may be prescribed for children and infants as young as a few days of age for selected conditions, precautions do apply. For infants, you may crush the tablet and place in a small amount of (5 to 10 mL or 1 to 2 teaspoonfuls) of water, breast milk, or non-soy based infant formula. Do not mix with soy-based infant formula. Give as directed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medication?
Keep out of the reach of children and pets. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Keep container tightly closed. Throw away any unused medication after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible: -Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat -Anxiety, nervousness -Excessive sweating or sensitivity to heat -Fever -Heart palpitations—rapid, pounding, or irregular heartbeat -Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing -Irregular menstrual cycles or spotting -Severe diarrhea -Tremors or shaking -Trouble sleeping Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): -Changes in appetite -Hair loss -Headache -Nausea -Vomiting
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions: -Addison disease -Adrenal gland problem -Bone problems -Chest pain -Diabetes -Dieting or on a weight loss program -Fertility problems -Heart disease -Pituitary gland problem -Take medications that treat or prevent blood clots -An unusual or allergic reaction to levothyroxine, other medications, foods, dyes, or preservatives -Pregnant or trying to get pregnant -Breastfeeding
What may interact with this medication?
-Amiodarone -Antacids -Calcium supplements -Carbamazepine -Certain medications for depression -Certain medications to treat cancer -Cholestyramine -Clofibrate -Colesevelam -Colestipol -Digoxin -Estrogen or progestin hormones -Iron supplements -Ketamine -Lanthanum -Liquid nutrition products, such as Ensure -Lithium -Medications for colds and breathing difficulties -Medications for diabetes -Medications or dietary supplements for weight loss -Methadone -Niacin -Orlistat -Oxandrolone -Phenobarbital or other barbiturates -Phenytoin -Rifampin -Sevelamer -Simethicone -Sodium polystyrene sulfonate -Soy isoflavones -Steroid medications, such as prednisone or cortisone -Sucralfate -Testosterone -Theophylline -Thyroid hormones -Warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse. It may be some time before you see the benefit from this medication. Do not switch brands of this medication unless your care team agrees with the change. Ask questions if you are uncertain. You may need blood work done while you are taking this medication. Biotin (vitamin B7) may interfere with your thyroid function test. Stop taking supplements that contain biotin 2 days before your blood work. This medication can affect blood sugar levels. If you have diabetes, check your blood sugar as directed.
What are the most serious risks of this medication?
This medicine is not to be used for weight loss. Large doses of this medicine can cause weight loss, but such doses can cause serious toxicity.
Source: This information is sourced from Elsevier Inc.
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Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.
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