Xalatan contains the active ingredient latanoprost in the form of a prostaglandin F analogue. It is formulated as an ophthalmic solution at a concentration of 0.005% for administration directly to the eyes. Key inactive ingredients include benzalkonium chloride, sodium chloride, and water for injection. This medication is intended to be used as a sterile, isotonic solution for eye care.

How should I use this medication?

This medication is only for use in the eye. Follow the directions on the prescription label. Wash hands before and after use. Tilt your head back slightly and pull your lower eyelid down with your index finger to form a pouch. Try not to touch the tip of the dropper or tube to your eye, fingertips, or other surfaces. Squeeze the prescribed number of drops into the pouch. Close the eye gently to spread the drops. Do not use your medication more often than directed. Finish the full course of medication prescribed by your care team even if you think your condition is better. Do not stop using except on the advice of your care team. If you are using another eye product, wait at least 5 minutes between use of this medication and the other eye product. Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

Where should I keep my medication?

Keep out of the reach of children and pets. See product label for storage information. Each product may have different instructions. Iyuzeh: Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Keep this medication in the foil pouch until you are ready to take it. Get rid of any unused medication after it expires or 30 days after opening the foil pouch, whichever is first. Xalatan: Store unopened bottles in the refrigerator. Once opened, it may be stored at room temperature between 20 and 25 degrees C (68 and 77 degrees F) for 6 weeks. Protect from light. Get rid of any unused medication after it expires or after 6 weeks at room temperature, whichever is first. To get rid of medications that are no longer needed or have expired: -Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location. -If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible: -Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat -Change in vision -New or worsening eye pain, redness, irritation, or discharge Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): -Blurry vision -Change in eye, eyelash, or eyelid color -Dry eyes -Eye irritation or itching -Increase in length, thickness, or number of eyelashes -Increased tears after use

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions: -Closed angle glaucoma -Eye injury, infection, or swelling -Wear contact lenses -An unusual or allergic reaction to latanoprost, other medications, foods, dyes, or preservatives -Pregnant or trying to get pregnant -Breastfeeding

What may interact with this medication?

This medication may interact with the following: -Bromfenac -Eye drops that contain thimerosal (a preservative)

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. Report any serious side effects right away. Stop using this medication if your eyes get swollen, painful, or have a discharge, and see your care team as soon as you can. This medication may cause your eye, eyelashes, and eyelids to change color. Tell your care team if this happens. If only one eye is being treated with this medication, a difference may develop between the treated and untreated eye in eyelash length, darkness or thickness, and color changes of the eyelid skin or iris. These changes may be permanent. If you wear contact lenses, take them out before placing drops in the eye. Contact lenses may be put back in 15 minutes after putting the drops in your eyes. Wear dark glasses if this medication makes your eyes more sensitive to light.